Ketamine augmentation of electroconvulsive therapy to improve neuropsychological and clinical outcomes in depression (Ketamine-ECT): a multicentre, double-blind, randomised, parallel-group, superiority trial

BACKGROUND: The use of electroconvulsive therapy (ECT) is limited by concerns about its cognitive adverse effects. Preliminary evidence suggests that administering the glutamate antagonist ketamine with ECT might alleviate cognitive adverse effects and accelerate symptomatic improvement; we tested t...

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Publicado no:Lancet Psychiatry
Main Authors: Anderson, Ian M, Blamire, Andrew, Branton, Tim, Clark, Ross, Downey, Darragh, Dunn, Graham, Easton, Andrew, Elliott, Rebecca, Elwell, Clare, Hayden, Katherine, Holland, Fiona, Karim, Salman, Loo, Colleen, Lowe, Jo, Nair, Rajesh, Oakley, Timothy, Prakash, Antony, Sharma, Parveen K, Williams, Stephen R, McAllister-Williams, R Hamish
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406618/
https://ncbi.nlm.nih.gov/pubmed/28359862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2215-0366(17)30077-9
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