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Cluster microRNAs miR‐194 and miR‐215 suppress the tumorigenicity of intestinal tumor organoids

Tumor stem cells with self‐renewal and multipotent capacity play critical roles in the initiation and progression of cancer. Recently, a new 3‐D culture system known as organoid culture has been developed, allowing Lgr5‐positive stem cells to form organoids that resemble the properties of original t...

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書目詳細資料
發表在:Cancer Sci
Main Authors: Nakaoka, Toshiaki, Saito, Yoshimasa, Shimamoto, Yuriko, Muramatsu, Toshihide, Kimura, Masaki, Kanai, Yae, Saito, Hidetsugu
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406536/
https://ncbi.nlm.nih.gov/pubmed/28092415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13165
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