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Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy
Inhibition of immune checkpoint molecules, PD‐1 and CTLA4, has been shown to be a promising cancer treatment. PD‐1 and CTLA4 inhibit TCR and co‐stimulatory signals. The third T cell activation signal represents the signals from the cytokine receptors. The cytokine interferon‐γ (IFNγ) plays an import...
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| Veröffentlicht in: | Cancer Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406529/ https://ncbi.nlm.nih.gov/pubmed/28188673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13194 |
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