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Hydroxywarfarin Metabolites Potently Inhibit CYP2C9 Metabolism of S-Warfarin
Coumadin (R/S-warfarin) anticoagulant therapy poses a risk to over 50 million Americans, in part due to interpersonal variation in drug metabolism. Consequently, it is important to understand how metabolic capacity is influenced among patients. Cytochrome P450s (P450 or CYP for a specific isoform) c...
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| Publicado no: | Chem Res Toxicol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406237/ https://ncbi.nlm.nih.gov/pubmed/20429590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1000283 |
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