RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection

The type I interferon pathway plays a critical role in both host defense and tolerance against viral infection and thus requires refined regulatory mechanisms. RIPK3-mediated necroptosis has been shown to be involved in anti-viral immunity. However, the exact role of RIPK3 in immunity to Influenza A...

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Publicado en:PLoS Pathog
Autores principales: Downey, Jeffrey, Pernet, Erwan, Coulombe, François, Allard, Benoit, Meunier, Isabelle, Jaworska, Joanna, Qureshi, Salman, Vinh, Donald C., Martin, James G., Joubert, Philippe, Divangahi, Maziar
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406035/
https://ncbi.nlm.nih.gov/pubmed/28410401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006326
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