In vitro and in vivo antivirus activity of an anti-programmed death-ligand 1 (PD-L1) rat-bovine chimeric antibody against bovine leukemia virus infection

Programmed death-1 (PD-1), an immunoinhibitory receptor on T cells, is known to be involved in immune evasion through its binding to PD-ligand 1 (PD-L1) in many chronic diseases. We previously found that PD-L1 expression was upregulated in cattle infected with bovine leukemia virus (BLV) and that an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Nishimori, Asami, Konnai, Satoru, Okagawa, Tomohiro, Maekawa, Naoya, Ikebuchi, Ryoyo, Goto, Shinya, Sajiki, Yamato, Suzuki, Yasuhiko, Kohara, Junko, Ogasawara, Satoshi, Kato, Yukinari, Murata, Shiro, Ohashi, Kazuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405919/
https://ncbi.nlm.nih.gov/pubmed/28445479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174916
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