Anti-Bovine Programmed Death-1 Rat–Bovine Chimeric Antibody for Immunotherapy of Bovine Leukemia Virus Infection in Cattle

Blockade of immunoinhibitory molecules, such as programmed death-1 (PD-1)/PD-ligand 1 (PD-L1), is a promising strategy for reinvigorating exhausted T cells and preventing disease progression in a variety of chronic infections. Application of this therapeutic strategy to cattle requires bovinized chi...

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Pubblicato in:Front Immunol
Autori principali: Okagawa, Tomohiro, Konnai, Satoru, Nishimori, Asami, Maekawa, Naoya, Ikebuchi, Ryoyo, Goto, Shinya, Nakajima, Chie, Kohara, Junko, Ogasawara, Satoshi, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461298/
https://ncbi.nlm.nih.gov/pubmed/28638381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00650
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