Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status

Three to eight percent of female carriers of Duchenne muscular dystrophy (DMD) develop dystrophic symptoms ranging from mild muscle weakness to a rapidly progressive DMD-like muscular dystrophy due to skewed inactivation of X chromosomes during early development. Here, we generated human induced plu...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Miyagoe-Suzuki, Yuko, Nishiyama, Takashi, Nakamura, Miho, Narita, Asako, Takemura, Fusako, Masuda, Satoru, Minami, Narihiro, Murayama, Kumiko, Komaki, Hirofumi, Goto, Yu-ichi, Takeda, Shin'ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405591/
https://ncbi.nlm.nih.gov/pubmed/28491099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7906843
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