The Pneumococcal Alpha-Glycerophosphate Oxidase Enhances Nasopharyngeal Colonization through Binding to Host Glycoconjugates

Streptococcus pneumoniae (the pneumococcus) is a major human pathogen, causing a broad spectrum of diseases including otitis media, pneumonia, bacteraemia and meningitis. Here we examined the role of a potential pneumococcal meningitis vaccine antigen, alpha-glycerophosphate oxidase (SpGlpO), in nas...

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Publicat a:EBioMedicine
Autors principals: Mahdi, Layla K., Higgins, Melanie A., Day, Christopher J., Tiralongo, Joe, Hartley-Tassell, Lauren E., Jennings, Michael P., Gordon, David L., Paton, Adrienne W., Paton, James C., Ogunniyi, Abiodun D.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405170/
https://ncbi.nlm.nih.gov/pubmed/28330602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.002
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