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Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice

Streptococcus pneumoniae is the most common cause of severe bacterial meningitis in children, the elderly, and immunocompromised individuals. To identify virulence factors preferentially expressed during meningitis, we conducted niche-specific genome-wide in vivo transcriptomic analysis after intran...

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Detalhes bibliográficos
Main Authors: Mahdi, Layla K., Wang, Hui, Van der Hoek, Mark B., Paton, James C., Ogunniyi, Abiodun D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366392/
https://ncbi.nlm.nih.gov/pubmed/22622042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45850
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