Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary Syndrome

Adult rats treated concomitantly with insulin and human chorionic gonadotropin exhibit endocrine, metabolic, and reproductive abnormalities that are very similar to those observed in polycystic ovary syndrome (PCOS) patients. In this study, we used this rat model to assess the effects of metformin o...

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Udgivet i:EBioMedicine
Main Authors: Zhang, Yuehui, Hu, Min, Meng, Fanci, Sun, Xiaoyan, Xu, Hongfei, Zhang, Jiao, Cui, Peng, Morina, Njomeza, Li, Xin, Li, Wei, Wu, Xiao-Ke, Brännström, Mats, Shao, Ruijin, Billig, Håkan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405166/
https://ncbi.nlm.nih.gov/pubmed/28336389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.023
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