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Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary Syndrome

Adult rats treated concomitantly with insulin and human chorionic gonadotropin exhibit endocrine, metabolic, and reproductive abnormalities that are very similar to those observed in polycystic ovary syndrome (PCOS) patients. In this study, we used this rat model to assess the effects of metformin o...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zhang, Yuehui, Hu, Min, Meng, Fanci, Sun, Xiaoyan, Xu, Hongfei, Zhang, Jiao, Cui, Peng, Morina, Njomeza, Li, Xin, Li, Wei, Wu, Xiao-Ke, Brännström, Mats, Shao, Ruijin, Billig, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405166/
https://ncbi.nlm.nih.gov/pubmed/28336389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.023
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