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Isolation of conditional mutations in genes essential for viability of Cryptococcus neoformans

Discovering the genes underlying fundamental processes that enable cells to live and reproduce is a technical challenge, because loss of gene function in mutants results in organisms that cannot survive. This study describes a forward genetics method to identify essential genes in fungi, based on th...

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Bibliographic Details
Published in:Curr Genet
Main Authors: Ianiri, Giuseppe, Boyce, Kylie J., Idnurm, Alexander
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405016/
https://ncbi.nlm.nih.gov/pubmed/27783209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-016-0659-2
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