T-cell receptor signaling activates an ITK/NF-κB/GATA-3 axis in T-cell lymphomas facilitating resistance to chemotherapy

PURPOSE: T-cell lymphomas are a molecularly heterogeneous group of non-Hodgkin lymphomas (NHL) that account for a disproportionate number of NHL disease-related deaths due to their inherent and acquired resistance to standard multiagent chemotherapy regimens. Despite their molecular heterogeneity an...

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Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Wang, Tianjiao, Lu, Ye, Polk, Avery, Chowdhury, Pinki, Zamalloa, Carlos Murga, Fujiwara, Hiroshi, Suemori, Koichiro, Beyersdorf, Niklas, Hristov, Alexandra C., Lim, Megan S., Bailey, Nathanael G., Wilcox, Ryan A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405012/
https://ncbi.nlm.nih.gov/pubmed/27780854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1996
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