A Single Center Phase II Study of Ixazomib in Patients with Relapsed or Refractory Cutaneous or Peripheral T-cell Lymphomas

The transcription factor GATA-3, highly expressed in many cutaneous and peripheral T-cell lymphomas, confers resistance to chemotherapy in a cell-autonomous manner. As GATA-3 is transcriptionally regulated by NF-κB, we sought to determine the extent to which proteasomal inhibition impairs NF-κB acti...

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Publicado en:Am J Hematol
Main Authors: Boonstra, Philip S., Avery, Polk, Brown, Noah, Hristov, Alexandra C., Bailey, Nathanael G., Kaminski, Mark S., Phillips, Tycel, Devata, Sumana, Mayer, Tera, Wilcox, Ryan A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116510/
https://ncbi.nlm.nih.gov/pubmed/28842936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24895
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