Pharmacogenetic associations of β1-adrenergic receptor polymorphisms with cardiovascular outcomes in the SPS3 trial

BACKGROUND AND PURPOSE: Functional polymorphisms (Ser49Gly and Arg389Gly) in ADRB1 have been associated with cardiovascular and β-blocker response outcomes. Herein we examined associations of these polymorphisms with Major Adverse Cardiovascular Events (MACE), with and without stratification by β-bl...

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Veröffentlicht in:Stroke
Hauptverfasser: Magvanjav, Oyunbileg, McDonough, Caitrin W., Gong, Yan, McClure, Leslie A., Talbert, Robert L., Horenstein, Richard B., Shuldiner, Alan R., Benavente, Oscar R., Mitchell, Braxton D., Johnson, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404951/
https://ncbi.nlm.nih.gov/pubmed/28351962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.015936
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