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A Post-Hoc Evaluation of a Sample Size Re-estimation in the SPS3 Study Running head: Evaluating the SPS3 Sample Size Re-Estimation

BACKGROUND/AIMS: The use of adaptive designs has been increasing in randomized clinical trials. Sample size re-estimation is a type of adaptation in which nuisance parameters are estimated at an interim point in the trial and the sample size re-computed based on these estimates. The Secondary Preven...

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Détails bibliographiques
Publié dans:Clin Trials
Auteurs principaux: McClure, Leslie A, Szychowski, Jeff M, Benavente, Oscar, Hart, Robert G, Coffey, Christopher S
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025324/
https://ncbi.nlm.nih.gov/pubmed/27094488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774516643689
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