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A Post-Hoc Evaluation of a Sample Size Re-estimation in the SPS3 Study Running head: Evaluating the SPS3 Sample Size Re-Estimation

BACKGROUND/AIMS: The use of adaptive designs has been increasing in randomized clinical trials. Sample size re-estimation is a type of adaptation in which nuisance parameters are estimated at an interim point in the trial and the sample size re-computed based on these estimates. The Secondary Preven...

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Detalhes bibliográficos
Publicado no:Clin Trials
Main Authors: McClure, Leslie A, Szychowski, Jeff M, Benavente, Oscar, Hart, Robert G, Coffey, Christopher S
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025324/
https://ncbi.nlm.nih.gov/pubmed/27094488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774516643689
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