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A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells

Despite the urgent need for assays to visualize insulin secretion there is to date no reliable method available for measuring insulin release from single cells. To address this need, we developed a genetically encoded reporter termed RINS1 based on proinsulin superfolder GFP (sfGFP) and mCherry fusi...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Schifferer, Martina, Yushchenko, Dmytro A., Stein, Frank, Bolbat, Andrey, Schultz, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404835/
https://ncbi.nlm.nih.gov/pubmed/28366620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.03.001
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