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ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches

As a result of the association of a common polymorphism (rs2231142, Q141K) in the ATP-binding cassette G2 (ABCG2) transporter with serum urate concentration in a genome-wide association study, it was revealed that ABCG2 is an important uric acid transporter. This review discusses the relevance of AB...

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Publicado en:Pharmgenomics Pers Med
Main Authors: Cleophas, MC, Joosten, LA, Stamp, LK, Dalbeth, N, Woodward, OM, Merriman, Tony R
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404803/
https://ncbi.nlm.nih.gov/pubmed/28461764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S105854
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