Pharmacokinetics and Pharmacodynamics of Minocycline against Acinetobacter baumannii in a Neutropenic Murine Pneumonia Model

Multidrug-resistant (MDR) Acinetobacter baumannii is increasingly more prevalent in nosocomial infections. Although in vitro susceptibility of A. baumannii to minocycline is promising, the in vivo efficacy of minocycline has not been well established. In this study, the in vivo activity of minocycli...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Zhou, Jian, Ledesma, Kimberly R., Chang, Kai-Tai, Abodakpi, Henrietta, Gao, Song, Tam, Vincent H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404596/
https://ncbi.nlm.nih.gov/pubmed/28264853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02371-16
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