Population Pharmacokinetic Analysis of Doripenem after Intravenous Infusion in Korean Patients with Acute Infections

We investigated the population pharmacokinetics (PK) of doripenem in Korean patients with acute infections and determined an appropriate dosing regimen using a Monte Carlo simulation for predicting pharmacodynamics (PD). Patients (n = 37) with a creatinine clearance (CL(CR)) of 20 to 50 ml/min or &g...

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Sparad:
Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Lee, Dong-Hwan, Kim, Yong Kyun, Jin, Kyubok, Kang, Myoung Joo, Joo, Young-Don, Kim, Yang Wook, Moon, Young Soo, Shin, Jae-Gook, Kiem, Sungmin
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404572/
https://ncbi.nlm.nih.gov/pubmed/28223378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02185-16
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