Population Pharmacokinetic Analysis of Doripenem after Intravenous Infusion in Korean Patients with Acute Infections

We investigated the population pharmacokinetics (PK) of doripenem in Korean patients with acute infections and determined an appropriate dosing regimen using a Monte Carlo simulation for predicting pharmacodynamics (PD). Patients (n = 37) with a creatinine clearance (CL(CR)) of 20 to 50 ml/min or &g...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lee, Dong-Hwan, Kim, Yong Kyun, Jin, Kyubok, Kang, Myoung Joo, Joo, Young-Don, Kim, Yang Wook, Moon, Young Soo, Shin, Jae-Gook, Kiem, Sungmin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404572/
https://ncbi.nlm.nih.gov/pubmed/28223378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02185-16
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