The Bifunctional Enzyme SpoT Is Involved in the Clarithromycin Tolerance of Helicobacter pylori by Upregulating the Transporters HP0939, HP1017, HP0497, and HP0471

Clarithromycin (CLA) is a commonly recommended drug for Helicobacter pylori eradication. However, the prevalence of CLA-resistant H. pylori is increasing. Although point mutations in the 23S rRNA are key factors for CLA resistance, other factors, including efflux pumps and regulation genes, are also...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Antimicrob Agents Chemother
Κύριοι συγγραφείς: Geng, Xiwen, Li, Wen, Chen, Zhenghong, Gao, Sizhe, Hong, Wei, Ge, Xiaoran, Hou, Guihua, Hu, Zhekai, Zhou, Yabin, Zeng, Beini, Li, Wenjuan, Jia, Jihui, Sun, Yundong
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2017
Θέματα:
Mechanisms of Resistance
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404559/
https://ncbi.nlm.nih.gov/pubmed/28242673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02011-16
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