Identifying the appropriate FISH criteria for defining MET copy number driven lung adenocarcinoma through oncogene overlap analysis

INTRODUCTION: MET gene copy number gain (CNG) may be a predictive biomarker for MET inhibition in lung cancer, but the most appropriate method and criteria for defining MET positivity are uncertain. METHODS: MET copy number was assessed by fluorescence in situ hybridization (FISH) in lung adenocarci...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Noonan, Sinéad A., Berry, Lynne, Lu, Xian, Gao, Dexiang, Barón, Anna E., Chesnut, Patrick, Sheren, Jamie, Dara, L. Aisner, Merrick, Dan, Doebele, Robert C., Varella-Garcia, Marileila, Camidge, D. Ross
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404374/
https://ncbi.nlm.nih.gov/pubmed/27262212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.04.033
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