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From PK/PD to QSP: Understanding the Dynamic Effect of Cholesterol-Lowering Drugs on Atherosclerosis Progression and Stratified Medicine

Current computational and mathematical tools are demonstrating the high value of using systems modeling approaches (e.g. Quantitative Systems Pharmacology) to understand the effect of a given compound on the biological and physiological mechanisms related to a specific disease. This review provides...

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Detalhes bibliográficos
Publicado no:Curr Pharm Des
Main Authors: Pichardo-Almarza, Cesar, Diaz-Zuccarini, Vanessa
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403958/
https://ncbi.nlm.nih.gov/pubmed/27592718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1381612822666160905095402
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