A Novel Spiro-Heterocyclic Compound Identified by the Silkworm Infection Model Inhibits Transcription in Staphylococcus aureus

Synthetic compounds are a vital source of antimicrobial agents. To uncover therapeutically effective antimicrobial agents from a chemical library, we screened over 100,000 synthetic compounds for in vitro antimicrobial activity against methicillin-resistant Staphylococcus aureus and evaluated the in...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Paudel, Atmika, Hamamoto, Hiroshi, Panthee, Suresh, Kaneko, Keiichi, Matsunaga, Shigeki, Kanai, Motomu, Suzuki, Yutaka, Sekimizu, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403886/
https://ncbi.nlm.nih.gov/pubmed/28487682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00712
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