The Role of Amino Acid Substitution in HepT Toward Menaquinone Isoprenoid Chain Length Definition and Lysocin E Sensitivity in Staphylococcus aureus

OBJECTIVES: Staphylococcus aureus Smith strain is a historical strain widely used for research purposes in animal infection models for testing the therapeutic activity of antimicrobial agents. We found that it displayed higher sensitivity toward lysocin E, a menaquinone (MK) targeting antibiotic, co...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Panthee, Suresh, Paudel, Atmika, Hamamoto, Hiroshi, Uhlemann, Anne-Catrin, Sekimizu, Kazuhisa
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479192/
https://ncbi.nlm.nih.gov/pubmed/32983054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02076
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