Chromosomal Alterations and Gene Expression Changes Associated with the Progression of Leukoplakia to Advanced Gingivobuccal Cancer

We present an integrative genome-wide analysis that can be used to predict the risk of progression from leukoplakia to oral squamous cell carcinoma (OSCC) arising in the gingivobuccal complex (GBC). We find that the genomic and transcriptomic profiles of leukoplakia resemble those observed in later...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Bhosale, Priyanka G., Cristea, Simona, Ambatipudi, Srikant, Desai, Rajiv S., Kumar, Rajiv, Patil, Asawari, Kane, Shubhada, Borges, Anita M., Schäffer, Alejandro A., Beerenwinkel, Niko, Mahimkar, Manoj B.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403767/
https://ncbi.nlm.nih.gov/pubmed/28433800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.03.008
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