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ROS1 fusions rarely overlap with other oncogenic drivers in non-small cell lung cancer

INTRODUCTION: Chromosomal rearrangements involving the ROS proto-oncogene 1 receptor tyrosine kinase gene (ROS1) define a distinct molecular subset of non-small cell lung cancer (NSCLC) with sensitivity to ROS1 inhibitors. Recent reports have suggested a significant overlap between ROS1 fusions and...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Lin, Jessica J., Ritterhouse, Lauren L., Ali, Siraj M., Bailey, Mark, Schrock, Alexa B., Gainor, Justin F., Ferris, Lorin A., Mino-Kenudson, Mari, Miller, Vincent A., Iafrate, Anthony J., Lennerz, Jochen K., Shaw, Alice T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403618/
https://ncbi.nlm.nih.gov/pubmed/28088512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2017.01.004
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