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The impact of ISGylation during Mycobacterium tuberculosis infection in mice

Mycobacterium tuberculosis infection results in 1.5 million deaths annually. Type I interferon (IFN) signaling through its receptor IFNAR correlates with increased severity of disease, although how this increases susceptibility to M. tuberculosis remains uncertain. ISG15 is one of the most highly in...

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Detalhes bibliográficos
Publicado no:Microbes Infect
Main Authors: Kimmey, Jacqueline M., Campbell, Jessica A., Weiss, Leslie A., Monte, Kristen J., Lenschow, Deborah J., Stallings, Christina L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403610/
https://ncbi.nlm.nih.gov/pubmed/28087453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2016.12.006
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