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A multi-shRNA vector enhances the silencing efficiency of exogenous and endogenous genes in human cells

RNA interference (RNAi) is a powerful technology for suppressing gene function. In most studies, small interfering RNAs (siRNAs) consist of one short hairpin RNA (shRNA) and, therefore, are often unable to achieve loss-of-function of their target genes. In the current study, an RNAi vector containin...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: Weng, Yanjie, Shi, Ying, Xia, Xi, Zhou, Wenjuan, Wang, Hongyan, Wang, Changyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403481/
https://ncbi.nlm.nih.gov/pubmed/28454290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5672
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