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shRNA Silencing of Endogenous FGF2 in Rat Hippocampus Increases Anxiety Behavior

BACKGROUND: The fibroblast growth factor (FGF) system has been implicated in the pathophysiology of mood disorders in humans and in affective behavior in animal models. However, the studies have been either correlative or involved exogeneous administration of FGF2. None of them have directly linked...

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Detalhes bibliográficos
Main Authors: Eren-Koçak, Emine, Turner, Cortney A., Watson, Stanley J., Akil, Huda
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046217/
https://ncbi.nlm.nih.gov/pubmed/21215386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.11.020
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