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Identification of capsazepine as a novel inhibitor of system x(c)(−) and cancer-induced bone pain
The cystine/glutamate antiporter has been implicated in a variety of cancers as a major mediator of redox homeostasis. The excess glutamate secreted by this transporter in aggressive cancer cells has been associated with cancer-induced bone pain (CIBP) from distal breast cancer metastases. High-thro...
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| Publicado no: | J Pain Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402992/ https://ncbi.nlm.nih.gov/pubmed/28458574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S125045 |
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