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Role of cleavage at the core-E1 junction of hepatitis C virus polyprotein in viral morphogenesis

In hepatitis C virus (HCV) polyprotein sequence, core protein terminates with E1 envelope signal peptide. Cleavage by signal peptidase (SP) separates E1 from the complete form of core protein, anchored in the endoplasmic reticulum (ER) membrane by the signal peptide. Subsequent cleavage of the signa...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Pène, Véronique, Lemasson, Matthieu, Harper, Francis, Pierron, Gérard, Rosenberg, Arielle R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402940/
https://ncbi.nlm.nih.gov/pubmed/28437468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175810
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