Humanin rescues cultured rat cortical neurons from NMDA-induced toxicity through the alleviation of mitochondrial dysfunction

N-methyl-D-aspartate (NDMA) receptor-mediated excitotoxicity has been implicated in a variety of pathological situations such as Alzheimer’s disease (AD) and Parkinson’s disease. However, no effective treatments for the same have been developed so far. Humanin (HN) is a 24-amino acid peptide origina...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Cui, Ai-Ling, Zhang, Ying-Hua, Li, Jian-Zhong, Song, Tianbin, Liu, Xue-Min, Wang, Hui, Zhang, Ce, Ma, Guo-Lin, Zhang, Hui, Li, Kefeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402890/
https://ncbi.nlm.nih.gov/pubmed/28458518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S133042
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