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ERBB2-mutated metastatic non-small cell lung cancer: response and resistance to targeted therapies

ERBB2/HER2 has long been recognized as an oncogenic driver in some breast and gastro-esophageal cancers, in which amplification of this gene confers sensitivity to treatment with ERBB2 directed agents. More recently, somatic mutations in ERBB2 have been reported in 1–2% of patients with lung adenoca...

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Dettagli Bibliografici
Pubblicato in:J Thorac Oncol
Autori principali: Chuang, Jody C., Stehr, Henning, Liang, Ying, Das, Millie, Huang, Jane, Diehn, Maximilian, Wakelee, Heather A., Neal, Joel W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402884/
https://ncbi.nlm.nih.gov/pubmed/28167203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2017.01.023
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