A FRET Sensor for Non-Invasive Imaging of Amyloid Formation in Vivo

Misfolding and aggregation of amyloidogenic polypeptides lie at the root of many neurodegenerative diseases. Whilst protein aggregation can be readily studied in vitro by established biophysical techniques, direct observation of the nature and kinetics of aggregation processes taking place in vivo i...

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Publicado no:Chemphyschem
Main Authors: Kaminski Schierle, Gabriele S., Bertoncini, Carlos W., Chan, Fiona T. S., van der Goot, Annemieke T., Schwedler, Stefanie, Skepper, Jeremy, Schlachter, Simon, van Ham, Tjakko, Esposito, Alessandro, Kumita, Janet R., Nollen, Ellen A. A., Dobson, Christopher M., Kaminski, Clemens F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402868/
https://ncbi.nlm.nih.gov/pubmed/21308945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201000996
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