Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into emergence and spread of multidrug resistance

Multidrug-resistant tuberculosis (MDR-TB), caused by drug resistant strains of Mycobacterium tuberculosis, is an increasingly serious problem worldwide. In this study, we examined a dataset of 5,310 M. tuberculosis whole genome sequences from five continents. Despite great diversity with respect to...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Manson, Abigail L., Cohen, Keira A., Abeel, Thomas, Desjardins, Christopher A., Armstrong, Derek T., Barry, Clifton E., Brand, Jeannette, Chapman, Sinéad B., Cho, Sang-Nae, Gabrielian, Andrei, Gomez, James, Jodals, Andreea M., Joloba, Moses, Jureen, Pontus, Lee, Jong Seok, Malinga, Lesibana, Maiga, Mamoudou, Nordenberg, Dale, Noroc, Ecaterina, Romancenco, Elena, Salazar, Alex, Ssengooba, Willy, Velayati, A. A., Winglee, Kathryn, Zalutskaya, Aksana, Via, Laura E., Cassell, Gail H., Dorman, Susan E., Ellner, Jerrold, Farnia, Parissa, Galagan, James E., Rosenthal, Alex, Crudu, Valeriu, Homorodean, Daniela, Hsueh, Po-Ren, Narayanan, Sujatha, Pym, Alexander S., Skrahina, Alena, Swaminathan, Soumya, Van der Walt, Martie, Alland, David, Bishai, William R., Cohen, Ted, Hoffner, Sven, Birren, Bruce W., Earl, Ashlee M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402762/
https://ncbi.nlm.nih.gov/pubmed/28092681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3767
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