A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis

RCAS avian viruses have been used to deliver oncogene expression and induce tumors in transgenic mice expressing the virus receptor TVA. Here we report the generation and characterization of a novel RCAS-Cre-IRES-PyMT (RCI-PyMT) virus designed to specifically knockout genes of interest in tumors gen...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Wang, Wei, Meng, Yanling, Dong, Bingning, Dong, Jie, Ittmann, Michael M., Creighton, Chad J., Lu, Yang, Zhang, Hong, Shen, Tao, Wang, Jianghua, Rowley, David R., Li, Yi, Chen, Fengju, Moore, David D., Yang, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402631/
https://ncbi.nlm.nih.gov/pubmed/28433771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.03.003
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