Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model

Cuprizone-induced demyelination in mice is a frequently used model in preclinical multiple sclerosis research. A recent quantitative clinically-targeted MRI method, fast macromolecular proton fraction (MPF) mapping demonstrated a promise as a myelin biomarker in human and animal studies with a parti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Khodanovich, Marina Yu, Sorokina, Irina V., Glazacheva, Valentina Yu, Akulov, Andrey E., Nemirovich-Danchenko, Nikolay M., Romashchenko, Alexander V., Tolstikova, Tatyana G., Mustafina, Lilia R., Yarnykh, Vasily L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402392/
https://ncbi.nlm.nih.gov/pubmed/28436460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46686
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