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MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis

Articular cartilage injury can result in chondrocyte loss and diminishment of specialised extracellular matrix, which can progress to an osteoarthritic (OA) phenotype. Stem cells have emerged as a favourable approach for articular cartilage regeneration. Identification of miRNAs which influence stem...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Budd, Emma, de Andrés, María C., Sanchez-Elsner, Tilman, Oreffo, Richard O. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402270/
https://ncbi.nlm.nih.gov/pubmed/28436462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46704
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