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Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease.

Double-labeling immunohistochemistry was used to investigate the topographical relationship between beta-amyloid and tau protein epitopes present in cells bearing neurofibrillary tangles found in the hippocampal formation of patients with Alzheimer disease. An antiserum raised against the amino term...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Spillantini, M G, Goedert, M, Jakes, R, Klug, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1692627/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3952
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