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The solubilization of model Alzheimer tangles: reversing the beta-sheet conformation induced by aluminum with silicates.

Neurofibrillary tangles are one of two lesions found in the brain of Alzheimer disease victims. With synthetic peptide fragments of human neurofilament NF-M17 (Glu-Glu-Lys-Gly-Lys-Ser-Pro- Val-Pro-Lys-Ser-Pro-Val-Glu-Glu-Lys-Gly, phosphorylated and unphosphorylated), CD studies were done to examine...

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Detalles Bibliográficos
Main Authors: Fasman, G D, Moore, C D
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC45201/
https://ncbi.nlm.nih.gov/pubmed/7972040
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