The solubilization of model Alzheimer tangles: reversing the beta-sheet conformation induced by aluminum with silicates.
Neurofibrillary tangles are one of two lesions found in the brain of Alzheimer disease victims. With synthetic peptide fragments of human neurofilament NF-M17 (Glu-Glu-Lys-Gly-Lys-Ser-Pro- Val-Pro-Lys-Ser-Pro-Val-Glu-Glu-Lys-Gly, phosphorylated and unphosphorylated), CD studies were done to examine...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1994
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.23.11232 |
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