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Differential Targeting of Hsp70 Heat Shock Proteins HSPA6 and HSPA1A with Components of a Protein Disaggregation/Refolding Machine in Differentiated Human Neuronal Cells following Thermal Stress

Heat shock proteins (Hsps) co-operate in multi-protein machines that counter protein misfolding and aggregation and involve DNAJ (Hsp40), HSPA (Hsp70), and HSPH (Hsp105α). The HSPA family is a multigene family composed of inducible and constitutively expressed members. Inducible HSPA6 (Hsp70B')...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Deane, Catherine A. S., Brown, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401876/
https://ncbi.nlm.nih.gov/pubmed/28484369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00227
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