Stress-triggered phase separation is an adaptive, evolutionarily tuned response

In eukaryotic cells, diverse stresses trigger coalescence of RNA-binding proteins into stress granules. In vitro, stress-granule-associated proteins can demix to form liquids, hydrogels, and other assemblies lacking fixed stoichiometry. Observing these phenomena has generally required conditions far...

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Bibliographic Details
Published in:Cell
Main Authors: Riback, Joshua A., Katanski, Christopher D., Kear-Scott, Jamie L., Pilipenko, Evgeny V., Rojek, Alexandra E., Sosnick, Tobin R., Drummond, D. Allan
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401687/
https://ncbi.nlm.nih.gov/pubmed/28283059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.027
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