Reversible, specific, active aggregates of endogenous proteins assemble upon heat stress

Heat causes protein misfolding and aggregation, and in eukaryotic cells triggers aggregation of proteins and RNA into stress granules. We have carried out extensive proteomic studies to quantify heat-triggered aggregation and subsequent disaggregation in budding yeast, identifying more than 170 endo...

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Publicado no:Cell
Main Authors: Wallace, Edward W.J., Kear-Scott, Jamie L., Pilipenko, Evgeny V., Schwartz, Michael H., Laskowski, Pawel R., Rojek, Alexandra E., Katanski, Christopher D., Riback, Joshua A., Dion, Michael F., Franks, Alexander M., Airoldi, Edoardo M., Pan, Tao, Budnik, Bogdan A., Drummond, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567705/
https://ncbi.nlm.nih.gov/pubmed/26359986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.041
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