Olig1 is required for Noggin-induced neonatal myelin repair

OBJECTIVE: Neonatal white matter injury (NWMI) is a lesion found in preterm infants that can lead to cerebral palsy. Although antagonists of bone morphogenetic protein (BMP) signaling, such as Noggin, promote oligodendrocyte precursor cell (OPC) production after hypoxic-ischemic injury, the downstre...

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Publicat a:Ann Neurol
Autors principals: Sabo, Jennifer K., Heine, Vivi, Silbereis, John C., Schirmer, Lucas, Levison, Steven W., Rowitch, David H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401646/
https://ncbi.nlm.nih.gov/pubmed/28253550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24907
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