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Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11βHSD2-dependent mechanism
Glucocorticoids (GCs) are administered to human fetuses at risk of premature delivery and to infants with life-threatening respiratory and cardiac conditions. However, there are ongoing concerns about adverse effects of GC treatment on the developing human brain, although the precise molecular mecha...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631296/ https://ncbi.nlm.nih.gov/pubmed/19164857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36376 |
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