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Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11βHSD2-dependent mechanism

Glucocorticoids (GCs) are administered to human fetuses at risk of premature delivery and to infants with life-threatening respiratory and cardiac conditions. However, there are ongoing concerns about adverse effects of GC treatment on the developing human brain, although the precise molecular mecha...

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Detalhes bibliográficos
Main Authors: Heine, Vivi M., Rowitch, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631296/
https://ncbi.nlm.nih.gov/pubmed/19164857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36376
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