How Evolution of Mutations Conferring Drug Resistance Affects Viral Dynamics and Clinical Outcomes of Cytomegalovirus-Infected Hematopoietic Cell Transplant Recipients

Infection with cytomegalovirus (CMV) remains a significant cause of morbidity and mortality among hematopoietic cell transplant (HCT) recipients. We describe two pediatric HCT recipients who developed persistent and severe drug-resistant CMV infections. CMV resistance to foscarnet and ganciclovir wa...

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Hlavní autoři: Springer, Kathryn L., Chou, Sunwen, Li, Shaobing, Giller, Roger H., Quinones, Ralph, Shira, James E., Weinberg, Adriana
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Virology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC540138/
https://ncbi.nlm.nih.gov/pubmed/15634973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.1.208-213.2005
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